{"id":154,"date":"2021-04-15T15:07:24","date_gmt":"2021-04-15T18:07:24","guid":{"rendered":"http:\/\/pequenoprincipe.org.br\/newsano5\/en\/?p=154"},"modified":"2021-04-22T11:24:48","modified_gmt":"2021-04-22T14:24:48","slug":"the-bone-marrow-transplantation-service-turns-10-years-old","status":"publish","type":"post","link":"https:\/\/pequenoprincipe.org.br\/newsano5\/en\/3\/the-bone-marrow-transplantation-service-turns-10-years-old\/","title":{"rendered":"The Bone Marrow Transplantation Service turns 10 years old"},"content":{"rendered":"\n<p>Enzo Eliseu arrived at Pequeno Pr\u00edncipe Hospital in 2015 when he was only two months old, weighing less than 4,40lb. Despite his young age, the boy was already fighting a long battle for life. Born in Bel\u00e9m (state of Par\u00e1), he had been referred for care in a hospital in S\u00e3o Paulo. However, after being diagnosed with a rare disease, he was sent to Pequeno Pr\u00edncipe seeking for the only treatment that could restore his health: a bone marrow transplant (BMT). \u201cThe doctors told us that there was no time to find a 100% compatible donor. So, I was the donor myself, with a 50% match,\u201d says her mother, Marcilene Oliveira Silva. The transplant was a success and the boy, now 5 years old, was able to overcome the severe malnutrition that threatened his life, as well as the rare disease. \u201cEnzo is here only because the Pequeno Pr\u00edncipe\u2019s team gave themselves integrally to him. They are angels in our lives,\u201d she declares, touched. &nbsp;<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" width=\"1024\" height=\"684\" src=\"http:\/\/pequenoprincipe.org.br\/newsano5\/en\/wp-content\/uploads\/sites\/2\/2021\/04\/Pauta_1_Enzo-3-1024x684.jpg\" alt=\"\" class=\"wp-image-152\" srcset=\"https:\/\/pequenoprincipe.org.br\/newsano5\/en\/wp-content\/uploads\/sites\/2\/2021\/04\/Pauta_1_Enzo-3-1024x684.jpg 1024w, https:\/\/pequenoprincipe.org.br\/newsano5\/en\/wp-content\/uploads\/sites\/2\/2021\/04\/Pauta_1_Enzo-3-300x200.jpg 300w, https:\/\/pequenoprincipe.org.br\/newsano5\/en\/wp-content\/uploads\/sites\/2\/2021\/04\/Pauta_1_Enzo-3-768x513.jpg 768w, https:\/\/pequenoprincipe.org.br\/newsano5\/en\/wp-content\/uploads\/sites\/2\/2021\/04\/Pauta_1_Enzo-3.jpg 1200w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><br>Enzo\u2019s transplant is one of the 303 procedures performed during these 10 years of the BMT Service at the Pequeno Pr\u00edncipe. \u201cDuring this period, we have become one of the largest pediatric transplant centers in Latin America, especially in the area of allogenic transplants (when the transplanted cells come from another donor),\u201d highlights the doctor who implanted the service, Eur\u00edpides Ferreira.<\/p>\n\n\n\n<p>\u201cWhen Dr. Eur\u00edpides started to dream and design an oncology service, still in the early 1960s, he was a visionary. He was always ahead of his time, with a great capacity to set objectives and goals, and accomplish them. With a dedicated team, we have made a history of evolution of protection and care in health assistance, with technical scientific excellence, and humanized care, which culminated with the implantation of the Bone Marrow Transplantation Service,\u201d says the executive director of the Pequeno Pr\u00edncipe, Ety Cristina Forte Carneiro.<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"alignright size-large is-resized\"><img loading=\"lazy\" src=\"http:\/\/pequenoprincipe.org.br\/newsano5\/en\/wp-content\/uploads\/sites\/2\/2021\/04\/Pauta_1_TMO-2-1024x682.jpg\" alt=\"\" class=\"wp-image-136\" width=\"340\" height=\"226\" srcset=\"https:\/\/pequenoprincipe.org.br\/newsano5\/en\/wp-content\/uploads\/sites\/2\/2021\/04\/Pauta_1_TMO-2-1024x682.jpg 1024w, https:\/\/pequenoprincipe.org.br\/newsano5\/en\/wp-content\/uploads\/sites\/2\/2021\/04\/Pauta_1_TMO-2-300x200.jpg 300w, https:\/\/pequenoprincipe.org.br\/newsano5\/en\/wp-content\/uploads\/sites\/2\/2021\/04\/Pauta_1_TMO-2-768x512.jpg 768w, https:\/\/pequenoprincipe.org.br\/newsano5\/en\/wp-content\/uploads\/sites\/2\/2021\/04\/Pauta_1_TMO-2-1536x1024.jpg 1536w, https:\/\/pequenoprincipe.org.br\/newsano5\/en\/wp-content\/uploads\/sites\/2\/2021\/04\/Pauta_1_TMO-2-1568x1045.jpg 1568w, https:\/\/pequenoprincipe.org.br\/newsano5\/en\/wp-content\/uploads\/sites\/2\/2021\/04\/Pauta_1_TMO-2.jpg 2000w\" sizes=\"(max-width: 340px) 100vw, 340px\" \/><\/figure><\/div>\n\n\n\n<p><strong>Challenges&nbsp;<\/strong><br>Finding a compatible donor is one of the greatest challenges in performing a BMT. According to the service\u2019s chief physician, Carmem Maria Sales Bonfim, as the Brazilian population is highly mixed, the chances of finding a 100% compatible donor in the family is only 25%. \u201cAt the Pequeno Pr\u00edncipe, we have a person exclusively dedicated to this search. This coordinator can quickly identify the chances that a certain patient has to find a donor in the national or international banks. If this chance is small or the donor\u2019s availability is not immediate, we have the experience to proceed with other types of donors such as, for example, haploidentical donors (when the compatibility is not 100%) identified within the family itself,\u201d explains the doctor.<\/p>\n\n\n\n<p><strong>Rare diseases<\/strong><br>Two other major differentials, according to the doctor, are the care of young children and patients with rare diseases. This was the case of little Henry. The boy was born with the same rare disease as his brother and, since there were chances of him having the same diagnosis, his mother, Kelly Akemi Bueno, was monitored during the entire pregnancy. The family was integrated into a research project at the Pel\u00e9 Pequeno Pr\u00edncipe Research Institute, which investigates rare diseases and is coordinated by doctor and researcher Carolina Prando. With this, the boy\u2019s diagnosis was closed on his first day of life and he immediately began to receive the necessary care.<\/p>\n\n\n\n<p>When he was two months old, Henry underwent a bone marrow transplant and is having the opportunity to grow and develop in a healthy way. \u201cMy oldest son also had a BMT at age 3, but because his diagnosis was late, he was left with many sequelae. The early diagnosis, which was possible through the research, and the excellence of the Bone Marrow Transplantation Service\u2019s team, made all the difference in my youngest son\u2019s life,\u201d says the mother. Of all transplants performed in these 10 years, 26% were in children under 3 years old.<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"alignleft size-large is-resized\"><img loading=\"lazy\" src=\"http:\/\/pequenoprincipe.org.br\/newsano5\/en\/wp-content\/uploads\/sites\/2\/2021\/04\/Pauta_1_TMO-1-1024x682.jpg\" alt=\"\" class=\"wp-image-135\" width=\"340\" height=\"227\" srcset=\"https:\/\/pequenoprincipe.org.br\/newsano5\/en\/wp-content\/uploads\/sites\/2\/2021\/04\/Pauta_1_TMO-1-1024x682.jpg 1024w, https:\/\/pequenoprincipe.org.br\/newsano5\/en\/wp-content\/uploads\/sites\/2\/2021\/04\/Pauta_1_TMO-1-300x200.jpg 300w, https:\/\/pequenoprincipe.org.br\/newsano5\/en\/wp-content\/uploads\/sites\/2\/2021\/04\/Pauta_1_TMO-1-768x512.jpg 768w, https:\/\/pequenoprincipe.org.br\/newsano5\/en\/wp-content\/uploads\/sites\/2\/2021\/04\/Pauta_1_TMO-1-1536x1024.jpg 1536w, https:\/\/pequenoprincipe.org.br\/newsano5\/en\/wp-content\/uploads\/sites\/2\/2021\/04\/Pauta_1_TMO-1-1568x1045.jpg 1568w, https:\/\/pequenoprincipe.org.br\/newsano5\/en\/wp-content\/uploads\/sites\/2\/2021\/04\/Pauta_1_TMO-1.jpg 2000w\" sizes=\"(max-width: 340px) 100vw, 340px\" \/><\/figure><\/div>\n\n\n\n<p><strong>Multidisciplinary team<\/strong><br>The fact that Pequeno Pr\u00edncipe is a hospital that offers 32 specialties and counts on multidisciplinary teams is also determinant for the success of the BMT Service of the Hospital. \u201cThe service is provided by doctors trained in pediatric transplantation, who count on the daily support of professionals from other specialties, such as infectologists, intensivists, nephrologists, cardiologists, neurologists, endocrinologists, dermatologists, and hemotherapist. The multidisciplinary team is completed with psychologists, nutritionists, social workers, physical therapists, dentists, and pharmacists. The service also works in partnership with the intensive care units of the Pequeno Pr\u00edncipe, the Genomic Laboratory and the Research Institute, for instance. This teamwork guarantees a service of excellence and makes all the difference in the treatment of the patients and in the results of the transplants,\u201d says the doctor.<\/p>\n\n\n\n<p><strong>Future plans<\/strong><br>Implanted in April 2011, initially with three beds, the Pequeno Pr\u00edncipe Bone Marrow Transplantation Service was expanded in 2016, to include ten beds. Now, the goal is to inaugurate two more beds. \u201cWith this new expansion, we believe we will be able to transplant ten more patients per year,\u201d plans Carmen. In 2020, even with the coronavirus pandemic (COVID-19), the service performed 61 transplants, which is equivalent to 12% of the total pediatric bone marrow transplants performed in Brazil.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>During this period, 303 transplants were carried out on 280 patients, consolidating the service as one of the largest in Brazil to assist children through the Public Health System \u2013 SUS<\/p>\n","protected":false},"author":2,"featured_media":134,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[3],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/\/pequenoprincipe.org.br\/newsano5\/en\/wp-json\/wp\/v2\/posts\/154"}],"collection":[{"href":"https:\/\/pequenoprincipe.org.br\/newsano5\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pequenoprincipe.org.br\/newsano5\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pequenoprincipe.org.br\/newsano5\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pequenoprincipe.org.br\/newsano5\/en\/wp-json\/wp\/v2\/comments?post=154"}],"version-history":[{"count":8,"href":"https:\/\/pequenoprincipe.org.br\/newsano5\/en\/wp-json\/wp\/v2\/posts\/154\/revisions"}],"predecessor-version":[{"id":194,"href":"https:\/\/pequenoprincipe.org.br\/newsano5\/en\/wp-json\/wp\/v2\/posts\/154\/revisions\/194"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pequenoprincipe.org.br\/newsano5\/en\/wp-json\/wp\/v2\/media\/134"}],"wp:attachment":[{"href":"https:\/\/pequenoprincipe.org.br\/newsano5\/en\/wp-json\/wp\/v2\/media?parent=154"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pequenoprincipe.org.br\/newsano5\/en\/wp-json\/wp\/v2\/categories?post=154"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pequenoprincipe.org.br\/newsano5\/en\/wp-json\/wp\/v2\/tags?post=154"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}