{"id":1061,"date":"2026-04-23T16:25:31","date_gmt":"2026-04-23T19:25:31","guid":{"rendered":"https:\/\/pequenoprincipe.org.br\/newsano\/?post_type=news26en&p=1061"},"modified":"2026-04-27T10:52:03","modified_gmt":"2026-04-27T13:52:03","slug":"pequeno-principe-biobank-drives-unprecedented-discovery-on-neuroblastoma","status":"publish","type":"news26en","link":"https:\/\/pequenoprincipe.org.br\/newsano\/news26en\/pequeno-principe-biobank-drives-unprecedented-discovery-on-neuroblastoma\/","title":{"rendered":"Pequeno Pr\u00edncipe Biobank drives unprecedented discovery on neuroblastoma"},"content":{"rendered":"\n

A recent discovery in international science has provided new paths for the treatment of neuroblastoma<\/strong>, one of the most aggressive childhood cancers. Part of this advancement was possible thanks to the work carried out by the Pel\u00e9 Pequeno Pr\u00edncipe Research Institute, through its biobank.<\/p>\n\n\n\n

Researchers from the University of Queensland, in Australia, mapped with a high level of precision the functioning of neuroblastoma<\/strong>, a tumor that mainly affects young children and is among the leading causes of death from childhood cancer. The study identified mechanisms that help the tumor protect itself in the body \u2014 described as true \u201cshields\u201d and \u201cbodyguards\u201d \u2014 and, from this, pointed out new therapeutic possibilities<\/strong>, including with drugs that are already under development.<\/p>\n\n\n

\n
\"\"<\/figure>\n<\/div>\n\n\n

From the biobank to international research<\/strong><\/p>\n\n\n\n

The scientific advancement was only possible thanks to access to biological samples stored in the biobank of the Pel\u00e9 Pequeno Pr\u00edncipe Research Institute<\/strong>. Over the years, this collection has been gathering, with technical and ethical rigor, materials that today allow the conduct of high-complexity studies in partnership with international centers.<\/p>\n\n\n\n

In addition, scientist Cleber Machado<\/strong>, from Pequeno Pr\u00edncipe, is part of the group of researchers responsible for the study, reinforcing the institution\u2019s active participation in global scientific production.<\/p>\n\n\n\n

\u201cMore than support for research, the biobank represents a strategic choice of our institution, which is to invest in science as an integral part of healthcare<\/strong>,\u201d emphasizes the general director of the Research Institute, Ety Cristina Forte Carneiro.<\/p>\n\n\n

\n
\"\"<\/figure>\n<\/div>\n\n\n

When the knowledge becomes treatment<\/strong><\/p>\n\n\n\n

The research revealed that high-risk neuroblastoma tumors use sophisticated mechanisms to survive, including proteins that act as barriers against the natural destruction of cancer cells. By identifying these vulnerabilities, researchers paved the way for the development of more effective therapies \u2014 with the potential to reach clinical practice in the coming years.<\/p>\n\n\n\n

For children and families facing this diagnosis, this type of advancement represents more than a scientific discovery: it is a new possibility for treatment and concrete hope for better outcomes<\/strong>.<\/p>\n\n\n

\n
\"\"<\/figure>\n<\/div>\n\n\n

Science that is born from the support of society<\/strong><\/p>\n\n\n\n

An essential part of this trajectory is the support of society. Initiatives such as the Pequeno Pr\u00edncipe Gala<\/strong>, which has already allocated resources for the construction of the biobank, and projects made possible through Pronon (Brazilian National Program to Support Oncology Care)<\/strong>, with the participation of numerous companies, were decisive for its expansion and consolidation.<\/p>\n\n\n\n

Structures such as the biobank, often little visible to the public, are fundamental to enable research of this level. By organizing, preserving, and making samples available with quality and traceability, they allow knowledge to advance more rapidly, shortening the path between research and the patient.<\/p>\n\n\n\n

This funding model transforms social investment into concrete return for society<\/strong>: it accelerates scientific development, strengthens Brazil\u2019s autonomy in knowledge production, and reduces the time between discovery and its application in care. \u201cMore than supporting a cause, partners and donors make possible a virtuous cycle in which each resource invested in science multiplies into impact, reach, and transformed lives<\/strong>,\u201d highlights Ety.<\/p>\n","protected":false},"excerpt":{"rendered":"

Samples stored at the institution enabled international research that revealed how the tumor protects itself, opening paths for new treatments<\/p>\n","protected":false},"featured_media":1034,"parent":0,"menu_order":0,"template":"","edicao10_en":[46],"class_list":["post-1061","news26en","type-news26en","status-publish","has-post-thumbnail","hentry","edicao10_en-46","entry"],"acf":[],"gutenberg_blocks":[{"blockName":"core\/paragraph","attrs":[],"innerBlocks":[],"innerHTML":"\n

A recent discovery in international science has provided new paths for the treatment of neuroblastoma<\/strong>, one of the most aggressive childhood cancers. Part of this advancement was possible thanks to the work carried out by the Pel\u00e9 Pequeno Pr\u00edncipe Research Institute, through its biobank.<\/p>\n","innerContent":["\n

A recent discovery in international science has provided new paths for the treatment of neuroblastoma<\/strong>, one of the most aggressive childhood cancers. Part of this advancement was possible thanks to the work carried out by the Pel\u00e9 Pequeno Pr\u00edncipe Research Institute, through its biobank.<\/p>\n"]},{"blockName":null,"attrs":[],"innerBlocks":[],"innerHTML":"\n\n","innerContent":["\n\n"]},{"blockName":"core\/paragraph","attrs":[],"innerBlocks":[],"innerHTML":"\n

Researchers from the University of Queensland, in Australia, mapped with a high level of precision the functioning of neuroblastoma<\/strong>, a tumor that mainly affects young children and is among the leading causes of death from childhood cancer. The study identified mechanisms that help the tumor protect itself in the body \u2014 described as true \u201cshields\u201d and \u201cbodyguards\u201d \u2014 and, from this, pointed out new therapeutic possibilities<\/strong>, including with drugs that are already under development.<\/p>\n","innerContent":["\n

Researchers from the University of Queensland, in Australia, mapped with a high level of precision the functioning of neuroblastoma<\/strong>, a tumor that mainly affects young children and is among the leading causes of death from childhood cancer. The study identified mechanisms that help the tumor protect itself in the body \u2014 described as true \u201cshields\u201d and \u201cbodyguards\u201d \u2014 and, from this, pointed out new therapeutic possibilities<\/strong>, including with drugs that are already under development.<\/p>\n"]},{"blockName":null,"attrs":[],"innerBlocks":[],"innerHTML":"\n\n","innerContent":["\n\n"]},{"blockName":"core\/image","attrs":{"id":1034,"sizeSlug":"large","linkDestination":"none","align":"center"},"innerBlocks":[],"innerHTML":"\n

\"\"<\/figure>\n","innerContent":["\n
\"\"<\/figure>\n"]},{"blockName":null,"attrs":[],"innerBlocks":[],"innerHTML":"\n\n","innerContent":["\n\n"]},{"blockName":"core\/paragraph","attrs":{"fontSize":"small"},"innerBlocks":[],"innerHTML":"\n

From the biobank to international research<\/strong><\/p>\n","innerContent":["\n

From the biobank to international research<\/strong><\/p>\n"]},{"blockName":null,"attrs":[],"innerBlocks":[],"innerHTML":"\n\n","innerContent":["\n\n"]},{"blockName":"core\/paragraph","attrs":[],"innerBlocks":[],"innerHTML":"\n

The scientific advancement was only possible thanks to access to biological samples stored in the biobank of the Pel\u00e9 Pequeno Pr\u00edncipe Research Institute<\/strong>. Over the years, this collection has been gathering, with technical and ethical rigor, materials that today allow the conduct of high-complexity studies in partnership with international centers.<\/p>\n","innerContent":["\n

The scientific advancement was only possible thanks to access to biological samples stored in the biobank of the Pel\u00e9 Pequeno Pr\u00edncipe Research Institute<\/strong>. Over the years, this collection has been gathering, with technical and ethical rigor, materials that today allow the conduct of high-complexity studies in partnership with international centers.<\/p>\n"]},{"blockName":null,"attrs":[],"innerBlocks":[],"innerHTML":"\n\n","innerContent":["\n\n"]},{"blockName":"core\/paragraph","attrs":[],"innerBlocks":[],"innerHTML":"\n

In addition, scientist Cleber Machado<\/strong>, from Pequeno Pr\u00edncipe, is part of the group of researchers responsible for the study, reinforcing the institution\u2019s active participation in global scientific production.<\/p>\n","innerContent":["\n

In addition, scientist Cleber Machado<\/strong>, from Pequeno Pr\u00edncipe, is part of the group of researchers responsible for the study, reinforcing the institution\u2019s active participation in global scientific production.<\/p>\n"]},{"blockName":null,"attrs":[],"innerBlocks":[],"innerHTML":"\n\n","innerContent":["\n\n"]},{"blockName":"core\/paragraph","attrs":[],"innerBlocks":[],"innerHTML":"\n

\u201cMore than support for research, the biobank represents a strategic choice of our institution, which is to invest in science as an integral part of healthcare<\/strong>,\u201d emphasizes the general director of the Research Institute, Ety Cristina Forte Carneiro.<\/p>\n","innerContent":["\n

\u201cMore than support for research, the biobank represents a strategic choice of our institution, which is to invest in science as an integral part of healthcare<\/strong>,\u201d emphasizes the general director of the Research Institute, Ety Cristina Forte Carneiro.<\/p>\n"]},{"blockName":null,"attrs":[],"innerBlocks":[],"innerHTML":"\n\n","innerContent":["\n\n"]},{"blockName":"core\/image","attrs":{"id":1035,"sizeSlug":"large","linkDestination":"none","align":"center"},"innerBlocks":[],"innerHTML":"\n

\"\"<\/figure>\n","innerContent":["\n
\"\"<\/figure>\n"]},{"blockName":null,"attrs":[],"innerBlocks":[],"innerHTML":"\n\n","innerContent":["\n\n"]},{"blockName":"core\/paragraph","attrs":{"fontSize":"small"},"innerBlocks":[],"innerHTML":"\n

When the knowledge becomes treatment<\/strong><\/p>\n","innerContent":["\n

When the knowledge becomes treatment<\/strong><\/p>\n"]},{"blockName":null,"attrs":[],"innerBlocks":[],"innerHTML":"\n\n","innerContent":["\n\n"]},{"blockName":"core\/paragraph","attrs":[],"innerBlocks":[],"innerHTML":"\n

The research revealed that high-risk neuroblastoma tumors use sophisticated mechanisms to survive, including proteins that act as barriers against the natural destruction of cancer cells. By identifying these vulnerabilities, researchers paved the way for the development of more effective therapies \u2014 with the potential to reach clinical practice in the coming years.<\/p>\n","innerContent":["\n

The research revealed that high-risk neuroblastoma tumors use sophisticated mechanisms to survive, including proteins that act as barriers against the natural destruction of cancer cells. By identifying these vulnerabilities, researchers paved the way for the development of more effective therapies \u2014 with the potential to reach clinical practice in the coming years.<\/p>\n"]},{"blockName":null,"attrs":[],"innerBlocks":[],"innerHTML":"\n\n","innerContent":["\n\n"]},{"blockName":"core\/paragraph","attrs":[],"innerBlocks":[],"innerHTML":"\n

For children and families facing this diagnosis, this type of advancement represents more than a scientific discovery: it is a new possibility for treatment and concrete hope for better outcomes<\/strong>.<\/p>\n","innerContent":["\n

For children and families facing this diagnosis, this type of advancement represents more than a scientific discovery: it is a new possibility for treatment and concrete hope for better outcomes<\/strong>.<\/p>\n"]},{"blockName":null,"attrs":[],"innerBlocks":[],"innerHTML":"\n\n","innerContent":["\n\n"]},{"blockName":"core\/image","attrs":{"id":1036,"sizeSlug":"large","linkDestination":"none","align":"center"},"innerBlocks":[],"innerHTML":"\n

\"\"<\/figure>\n","innerContent":["\n
\"\"<\/figure>\n"]},{"blockName":null,"attrs":[],"innerBlocks":[],"innerHTML":"\n\n","innerContent":["\n\n"]},{"blockName":"core\/paragraph","attrs":{"fontSize":"small"},"innerBlocks":[],"innerHTML":"\n

Science that is born from the support of society<\/strong><\/p>\n","innerContent":["\n

Science that is born from the support of society<\/strong><\/p>\n"]},{"blockName":null,"attrs":[],"innerBlocks":[],"innerHTML":"\n\n","innerContent":["\n\n"]},{"blockName":"core\/paragraph","attrs":[],"innerBlocks":[],"innerHTML":"\n

An essential part of this trajectory is the support of society. Initiatives such as the Pequeno Pr\u00edncipe Gala<\/strong>, which has already allocated resources for the construction of the biobank, and projects made possible through Pronon (Brazilian National Program to Support Oncology Care)<\/strong>, with the participation of numerous companies, were decisive for its expansion and consolidation.<\/p>\n","innerContent":["\n

An essential part of this trajectory is the support of society. Initiatives such as the Pequeno Pr\u00edncipe Gala<\/strong>, which has already allocated resources for the construction of the biobank, and projects made possible through Pronon (Brazilian National Program to Support Oncology Care)<\/strong>, with the participation of numerous companies, were decisive for its expansion and consolidation.<\/p>\n"]},{"blockName":null,"attrs":[],"innerBlocks":[],"innerHTML":"\n\n","innerContent":["\n\n"]},{"blockName":"core\/paragraph","attrs":[],"innerBlocks":[],"innerHTML":"\n

Structures such as the biobank, often little visible to the public, are fundamental to enable research of this level. By organizing, preserving, and making samples available with quality and traceability, they allow knowledge to advance more rapidly, shortening the path between research and the patient.<\/p>\n","innerContent":["\n

Structures such as the biobank, often little visible to the public, are fundamental to enable research of this level. By organizing, preserving, and making samples available with quality and traceability, they allow knowledge to advance more rapidly, shortening the path between research and the patient.<\/p>\n"]},{"blockName":null,"attrs":[],"innerBlocks":[],"innerHTML":"\n\n","innerContent":["\n\n"]},{"blockName":"core\/paragraph","attrs":[],"innerBlocks":[],"innerHTML":"\n

This funding model transforms social investment into concrete return for society<\/strong>: it accelerates scientific development, strengthens Brazil\u2019s autonomy in knowledge production, and reduces the time between discovery and its application in care. \u201cMore than supporting a cause, partners and donors make possible a virtuous cycle in which each resource invested in science multiplies into impact, reach, and transformed lives<\/strong>,\u201d highlights Ety.<\/p>\n","innerContent":["\n

This funding model transforms social investment into concrete return for society<\/strong>: it accelerates scientific development, strengthens Brazil\u2019s autonomy in knowledge production, and reduces the time between discovery and its application in care. \u201cMore than supporting a cause, partners and donors make possible a virtuous cycle in which each resource invested in science multiplies into impact, reach, and transformed lives<\/strong>,\u201d highlights Ety.<\/p>\n"]}],"yoast_head":"\nPequeno Pr\u00edncipe Biobank drives unprecedented discovery on neuroblastoma - Newsletter HPP<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pequenoprincipe.org.br\/newsano\/news26en\/pequeno-principe-biobank-drives-unprecedented-discovery-on-neuroblastoma\/\" \/>\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pequeno Pr\u00edncipe Biobank drives unprecedented discovery on neuroblastoma - 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